The TFC Peptide Guide: 33 Compounds, Sourced and Graded

Peptides are the questions our inbox asks most, and the topic where good information is hardest to find. Today we are doing something about the second half of that sentence.

The TFC Peptide Guide is live: thirty-three compounds, sourced and graded, in one reference book. It costs $24, or £19, it is a PDF you keep forever, and every future update is free. It lives here.

The problem with peptide information

Type any peptide name into a search engine and read the top results. Now scroll to the bottom of each page and find the shop link, the discount code, or the "trusted vendor" list. Almost every peptide guide on the internet is a funnel for somebody selling peptides. The information and the commerce are the same document, and it shows in the claims.

This year it went further than framing. In February 2026 a peptide seller planted eight fake clinical trial registrations on ClinicalTrials.gov, the US government trials registry. Three of them admit it in their own text, one opening with the sentence "This fictional study is an example of a ClinicalTrials.gov-style record". The others read like real trials. Months later, all eight still showed as recruiting, and commercial trial databases had ingested them as genuine. The guide covers the whole episode, names the pattern, and disarms the fake records compound by compound where they touch the book.

That is the environment a curious person is researching in. It is why this book exists.

What the guide is

A reference work, built to be looked up rather than read cover to cover. Every one of the thirty-three profiles follows the same fixed schema: what the molecule actually is, the mechanism properly explained, what has genuinely been measured in humans and in animals, the evidence use by use, what nobody has measured yet, where the marketing runs ahead of the record, and its legal and sport status in plain terms.

At the front sits a comparison table across all thirty-three compounds, graded on a closed five-phrase evidence scale, from meta-analysis down to no published study in this use. The grade describes how much is known, never whether to take something. A compound at meta-analysis is not better than one at animal studies. It is better known. That distinction runs through the whole book.

The regulatory chapters were built from the primary record: the Federal Register notice, the FDA's own briefing packages for the July 2026 advisory committee votes, the official voting questions and the final meeting roster, and the WADA Prohibited List in force [1][2][3]. Reading the documents instead of the coverage corrected the public account of 2026 in several places, including how many people could actually vote and what is genuinely on the agenda for the committee's next meeting, expected by the end of February 2027 [4].

What the guide is not

There are no doses in the book. Not a quantity, not a frequency, not a cycle length, not an injection method. Regulators have found that up to 40% of online peptide products contained incorrect quantities or undeclared ingredients, and around a quarter contained compounds not on the label at all. You cannot dose a product whose contents you cannot verify, and a book that pretended otherwise would be selling you confidence it has no right to.

There are no vendor names and no purchase pathways. Education only. We do not sell peptides, we take no commission from anyone who does, and nobody paid for a place in the book. What you get instead is a chapter teaching you to judge any provider yourself: what a licensed prescriber looks like, what a real certificate of analysis is, and the questions that end a conversation with a seller.

The living edition

The regulatory ground under these compounds is actively moving. Votes happened in July 2026, rulemaking grinds on, and the next committee meeting is expected by February 2027 with five substances on FDA's published agenda, two of which have full profiles in this book. When the record changes, the book changes, and your download link always serves the current version. The edition history in Appendix C records exactly what changed and when.

Get The TFC Peptide Guide, $24 / £19. Thirty-three compounds, every claim sourced, every peptide graded by the strength of its evidence.